Association between hepatoblastoma and polyposis coli.
نویسندگان
چکیده
منابع مشابه
Association between hepatoblastoma and polyposis coli.
We have identified five children with hepatoblastoma who have a family history of polyposis coli affecting the mother and maternal relatives. We believe that the familial association of these two conditions is unlikely to have occurred by chance. Cytogenetic studies on three of the families have shown no evidence of a chromosomal abnormality.
متن کاملLessons from the hepatoblastoma-familial polyposis connection.
BACKGROUND Approximately one-third of hepatoblastoma (HB) patients have associated congenital abnormalities, but familial recurrence is rare, except in association with familial adenomatous polyposis (FAP). This correlation may be missed if not actively sought, with implications for long-term outcome and management. METHODS We retrospectively investigated 3 families with an HB-familial polypo...
متن کاملHepatoblastoma and APC gene mutation in familial adenomatous polyposis
Background-Hepatoblastoma is a rare, rapidly progressive, usually fatal childhood malignancy, which if confined to the liver can be cured by radical surgical resection. An association between hepatoblastoma and familial adenomatous polyposis (FAP), which is due to germline mutation of the APC (adenomatous polyposis coli) gene, has been confirmed, but correlation with site ofAPC mutation has not...
متن کاملHepatoblastoma and APC gene mutation in familial adenomatous polyposis.
BACKGROUND Hepatoblastoma is a rare, rapidly progressive, usually fatal childhood malignancy, which if confined to the liver can be cured by radical surgical resection. An association between hepatoblastoma and familial adenomatous polyposis (FAP), which is due to germline mutation of the APC (adenomatous polyposis coli) gene, has been confirmed, but correlation with site of APC mutation has no...
متن کاملJuvenile polyposis coli.
The term 'polyposis coli' applies to a condition of multiple polyps of the large intestine and is used synonymously with 'familial polyposis' and 'multiple adenomatosis'. The latter name emphasizes the fact that the individual polyps of this disease in no way differ from adenomas observed as solitary lesions. The object of this paper is to describe the histopathology, clinical features, and fam...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1983
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.58.12.959